• br Lineage tracing tools for

  2018-11-06

  

  Lineage tracing tools for investigating stem cell biology The investigation of cell lineage involves labeling cgrp antagonist of interest, then tracing the destiny of their progeny. The reliance on the presence of cell markers alone to infer the origin or fate of a cell population is fallible, as

• We have demonstrated that neuregulin induced proliferation o

  2018-11-06

  

  We have demonstrated that neuregulin-induced proliferation of differentiated adult mouse and rat cardiomyocytes occurs primarily in the mononucleated portion (Bersell et al., 2009). Most adult zebrafish cardiomyocytes are mononucleated, which is consistent with their significant proliferative activi

• CXCL has been previously identified as an estrogen

  2018-11-06

  

  CXCL12 has been previously identified as an estrogen-regulated gene in estrogen receptor (ER)-positive ovarian and breast cancer Phenyl sulfate (Jaerve et al., 2012). Here we show that in the endometrium, E2 significantly increased CXCL12 expression, suggesting a mechanism by which stem cells are r

• Epiretinal transplantation does not involve retinal detachme

  2018-11-06

  

  Epiretinal transplantation does not involve retinal detachment and may cause less trauma to the retina as compared with subretinal cell delivery. However vitreous detachment in patients causes increased photopsias, floaters and increased risk of retinal detachment and macular holes (de Smet et al.,

• br Materials and methods br Author

  2018-11-06

  

  Materials and methods Author disclosure statement Acknowledgments We are grateful to Prof. Angel Raya for his help and advice with iPS cell generation. This work was supported by grants from the “Centro de Investigación Biomédica en Red en Enfermedades Raras” (CIBERER) (grant 13-717/132.05

• WP1130 Main Text In this issue of Stem Cell Reports two

  2018-11-05

  

  Main Text In this issue of Stem Cell Reports, two critically important studies describe negative results of a neural stem cell (NSC) product (HuCNS-SC) intended for clinical use in a model of cervical spinal cord injury (SCI) (Anderson et al., 2017) and in a model of Alzheimer’s disease (Marsh et a

• Introduction The phospho proteome in

  2018-11-05

  

  Introduction The phospho-proteome in pluripotent stem tgf beta receptor inhibitor has been extensively and systematically studied (Van Hoof et al., 2012), and has uncovered phosphorylated residues on pluripotency factors that play important roles in establishing and maintaining pluripotency. Despi

• While the preponderance of evidence

  2018-11-05

  

  While the preponderance of evidence thus far has linked religiosity and health in a positive way, effects are not universally beneficial. Certain aspects and measures of religiosity have been shown to be disadvantages to health. For instance, religion has been found to induce anxiety when it order

• Methodological advances in bereavement research in recent

  2018-11-05

  

  Methodological advances in bereavement research in recent years have improved the quality of research outputs, not least through the introduction of the Integrated Risk Factor Framework (IRFF) (Stroebe, Folkman, Hansson, & Schut, 2006). A key feature of this framework is that variables from a number

• In our case we test if attitudes

  2018-11-05

  

  In our case, we test if attitudes toward cut and uncut girls differ between Sudanese people living in Switzerland versus Sudan. This is a test of the joint effect of selection and acculturation. We additionally analyze variation in attitudes within Switzerland, including an analysis of whether attit

• Increased neuronal activation could lead to cellular swellin

  2018-11-05

  

  Increased neuronal activation could lead to cellular swelling and also activity-dependent myelin-modulation via increased astrocyte activity (Messina et al., 2015), which could account for the diffusion alterations in our findings. Therefore, one plausible and perhaps most likely explanation for our

• Using the Cox regression model GOI with the

  2018-11-05

  

  Using the Cox regression model, 30 GOI with the new reference distribution of gene-expression levels, it was possible to distinguish mastectomy patients into the LRR low/high risk groups for the data set published in 2006 (Table 2) (Cheng et al., 2006b). This 30-gene panel could also distinguish the

• nadph oxidase inhibitor br Skin and Hair Aging Lifestyle and

  2018-11-05

  

  Skin and Hair Aging, Lifestyle and the Skin and Scalp Microbiomes William W. Mohn (Vancouver, Canada) reported on a cross-sectional study investigating the skin and scalp microbiome in relation to skin and hair aging and lifestyle, and involving 495 subjects 10–78years of age. Diversity of the sc

• Animal studies of myopia have shown that

  2018-11-05

  

  Animal studies of myopia have shown that atropine—a non-selective muscarinic ionophores receptor (mAChR) antagonist—effectively prevents the axial elongation, leading to myopia (Fan et al., 2007; Rada et al., 2000; Shih et al., 1999). Atropine inhibits myopia progression in the tree shrew, monkey,

• SGX523 Because only transient exposure of

  2018-11-05

  

  Because only transient exposure of melanoma SGX523 to pevonedistat is sufficient to irreversibly arrest melanoma cells with the majority of cells undergoing senescence, and this occurs only in malignant melanoma cells, targeting the CRL4CDT2 ubiquitin ligase is an especially attractive therapeutic

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