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El proyecto literario del conocido
2019-06-17
El proyecto literario del conocido escritor mexicano Ignacio Manuel Altamirano (1834–1893) ha sido ampliamente documentado en los estudios del siglo . Su propósito fue claro: instruir e inspirar al pueblo mexicano, cansado y desilusionado por la situación inestable del México decimonónico y por el s
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order Amikacin En este art culo se observar n ciertos puntos
2019-06-17
En este artículo se observarán ciertos puntos de los capítulos IX y X de Paradiso, donde el autor claramente se rehúsa order Amikacin definir a sus personajes y sus discursos, para plantear interrogantes y momentos paradigmáticos de esta imposibilidad clasificatoria que era el objetivo (o utopía) de
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br LEGADO FUJIMORISTA No seu segundo mandato Garc a abandono
2019-06-17
LEGADO FUJIMORISTA No seu segundo mandato, García abandonou as veleidades esquerdistas realizando um governo abertamente neoliberal. Embora em campanha criticasse o modelo de exploração mineira em que se assentava o crescimento peruano, praticamente eximindo as empresas de obrigações tributárias
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Introduction Acute acalculous cholecystitis ACC is defined a
2019-06-17
Introduction Acute acalculous cholecystitis (ACC) is defined as an acute necroinflammatory disease of the gallbladder in the absence of cholelithiasis and has a multifactorial pathogenesis [1]. ACC has very rarely been described in patients undergoing myelosuppressive chemotherapy for acute myelobl
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Although the CHADS score is useful
2019-06-17
Although the CHADS2 score is useful for evaluating the risk of stroke in NVAF patients, about half of all NVAF patients have a score of or 1 [7]. There are no clear guidelines on whether warfarin should be administered or not, to these patients because the risk of annual incidence of stroke is so lo
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Introduction Despite advances in breast cancer treatment bon
2019-06-17
Introduction Despite advances in breast cancer treatment, bone remains the most common site of SCH772984 TFA manufacturer [1,2] occurring in around 70% of patients with metastatic disease [3]. Bone metastases are incurable and associated with significant morbidity in terms of fractures, pain, and r
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Worldwide one in three women experience gender based violenc
2019-06-15
Worldwide, one in three women experience gender-based violence, which imparts physical, mental, and sexual health morbidities. It also causes mortality—more than a third of homicides of women are attributable to male partners. These data justifiably create global outrage, accentuated by horrific rec
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A possible mechanism of the initiation of HSTCL is a
2019-06-15
A possible mechanism of the CB-5083 of HSTCL is a prolonged immunosuppressive status which generates the expansion of γδ T-cells recognizing multiple pathogens through excessive antigenic stimulation. Our cases did not have any previous illness related to immunosuppression, recurrent infectious epi
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molarity and dilution br CaMKII and heart failure progressio
2019-06-15
CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com
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Atrial fibrillation AF is the most
2019-06-15
Atrial fibrillation (AF) is the most common type of arrhythmia in developed countries. Its prevalence almost doubles with each decade of life [1], with a lifetime prevalence of 25% [2]. AF is also an important risk factor for mortality [3]. Along with stroke, heart failure (HF), which is a signific
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br Clinical evidence to support that PES
2019-06-15
Clinical evidence to support that PES predicts cardiac events in BS Brugada et al. were the first to propose that inducibility of sustained ventricular arrhythmias with PES is useful to identify patients who are at high risk of SCD [3]. During follow-up of patients with spontaneous type 1 Brugada
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The renin angiotensin system plays a crucial role in atrial
2019-06-15
The renin-angiotensin system plays a crucial role in atrial fibrosis, which is a key pathological consequence of AF. Genes encoding 3 molecules related to the renin-angiotensin system, including angiotensin-converting enzyme (ACE), angiotensinogen, and angiotensin type 1 receptor (AT1R), are associa
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galanin receptor br Methods We reviewed http www canadiancan
2019-06-15
Methods We reviewed http://www.canadiancancertrials.ca/ and http://www.ontario.canadiancancertrials.ca/ in order to identify ongoing bone oncology-related trials. We used the keywords: bone, bone metastasis, bone treatment, cancer therapy induced bone loss and bisphosphonates for searching. We al
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Bepridil is a multichannel blocker suggesting
2019-06-15
Bepridil is a multichannel blocker, suggesting that its pharmacological effects on cardiac myocytes are exerted by blocking Na [21], Ca [22], and K [23–25] channels. It has recently been reported that bepridil has a cardioprotective effect [26] by opening ATP-dependent K semagacestat in mitochondria
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br Materials and methods br Results CRT devices were
2019-06-15
Materials and methods Results CRT devices were successfully implanted in 27 patients (70.7±10.1 years), and the LV leads were placed in the lateral branch or posterolateral branch. Baseline characteristics of all patients are listed in Table 1. Eighteen of 27 patients received a CRT defibrilla
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