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br Introduction Quenchbody Q body
2023-12-18
Introduction Quenchbody (Q-body) immunoassay is a novel biosensing technology that uses the quenching of fluorescence by intrinsic tryptophan (Trp) residues in antibody variable regions when dye(s) are conjugated to an antibody or antibody fragments in appropriate position, and de-quenching while
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Cy3.5 maleimide Platelet derived growth factor PDGF and
2023-12-18
Platelet-derived growth factor (PDGF) and ciliary neurotrophic factor (CNTF) are expressed by glial Cy3.5 maleimide and are important to neuron survival and the maintenance of oligodendrocytes. These neurotrophic factors contribute to the remyelination process by increasing the proliferation of oli
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Amyloid β-Peptide (1-42) Dose Response Studies Against Purom
2023-12-18
Dose–Response Studies Against Puromycin–Sensitive Aminopeptidase (PSA). PSA is a ubiquitous metallopeptidase encoded by the NPEPPS gene with subcellular distribution in the cytosol and nucleus [49]. Comprising of a 919 amino Amyloid β-Peptide (1-42) sequence, it has a broad substrate specificity, a
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br Materials and methods br Results br Discussion Prostate c
2023-12-18
Materials and methods Results Discussion Prostate cancer is the most common cancer in men in the United States and the second leading cause of cancer death. Therapeutic interventions include mainly: radical prostatectomy or radiation therapy (RT), with or without androgen deprivation therap
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br Materials and methods br Results br
2023-12-16
Materials and methods Results Discussion Competing financial interests Acknowledgements The work was partially supported by grants from the National Natural Science Foundation of China (Grant no. 31530053 and 31401424) and National Science and Technology Support Plan (Grant no. 2013BA
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br Discussion Here we show opposing effects of iontophoretic
2023-12-16
Discussion Here, we show opposing effects of iontophoretically administered phenylephrine,aselective α1-AR agonist, on firing of putatively DAergic and non-DAergic neurons recorded in vivo in the VTA of urethane anaesthetized rats. Phenylephrine application caused a relatively weak decrease in fi
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As the close paralog of adiponectin we hypothesized that
2023-12-16
As the close paralog of adiponectin, we hypothesized that CTRP9 could participate in regulation of reproduction. In order to evaluate whether Ctrp9 plays a role in the control of reproduction in tilapia, i.p. injection experiment was performed. HPG (Hypothalamic/pituitary/gonadal) axis plays a key r
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AXL is a member of the TAM Tyro
2023-12-16
AXL is a member of the TAM (Tyro3, Axl, Mer) family of receptor tyrosine kinases (RTKs) [4]. Elevated AXL expression could promote oncogenic processes such as cell growth, migration, invasion, and epithelial-to-mesenchymal transition (EMT), which substantially contribute to tumor progression and poo
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There are in contrast many studies
2023-12-16
There are in contrast many studies demonstrating that sex steroids modulate ML130 sale processing of stimuli related to reproduction and this correlates with the observation that steroid receptors and aromatase are expressed in many brain nuclei that are part of the olfactory, visual and auditory pa
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Placental cells also express P aromatase CYP A encoded by
2023-12-16
Placental cells also express P450 aromatase (CYP19A1, encoded by CYP19A1). In the placenta, this enzyme requires an external source of androgens, provided by the adrenal gland of the fetus, to form estrogen. The fetal adrenal gland produces dehydroepiandrosterone (DHEA) [9] and, in the placenta, it
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br Material and methods br
2023-12-16
Material and methods Results Discussion Asparagine, arginine, leucine, methionine, and glutamine are the essential buy penicillin for cancer cells and intensively investigated for the development of selective targeted therapeutics. Among them, asparagine depleting bacterial enzyme asparagin
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br Antioxidant polymers conjugates Natural
2023-12-16
Antioxidant-polymers conjugates Natural antioxidants are usually used as a substitute for synthetics but some degradation phenomena could influence their applications. For example, ascorbic Elacridar as a natural antioxidant undergoes yellowish coloration as a result of oxidation [29]. Sing and K
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Although the earlier studies focused on
2023-12-16
Although the earlier studies focused on the antioxidant capacity of tocopherols, ascorbic Sotrastaurin and carotenoids, then it was noticed that phenolic compounds were more powerful than others (Rice-Evans, Miller, & Paganga, 1996). Phenolic compounds, the most numerous and ubiquitous groups of pla
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Numerous investigators have shown that RACK
2023-12-16
Numerous investigators have shown that RACK1 has several important, possibly related, roles in mRNA splicing and in translation. RACK1 interacts directly with specific components of the 40S ribosomal subunit (specifically, the 18S rRNA and ribosomal proteins rpS16e, rpS17e, and rpS3e [new names: uS9
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br Experimental section br Acknowledgements The authors than
2023-12-16
Experimental section Acknowledgements The authors thank Prof. Yongbing Cao from School of Pharmacy, the Second Military Medical University, for providing the fluconazole-resistant strains of Candida albicans(strain 100 and strain 103). This work was supported by Program for Innovative Research
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