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SV trafficking is affected in Syn knocked
2018-10-23
SV trafficking is affected in αSyn knocked out and transgenic mice, suggesting αSyn role in neurotransmission (Esposito et al., 2012). At short time of incubation of neurons with αSyn, the observed increase in SV mobilization and fusion may correlate to the increased calcium influx. Instead, at late
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Substantial epidemics and sporadic outbreaks of hepatitis
2018-10-23
Substantial epidemics and sporadic outbreaks of hepatitis E occur in tropical and sub-tropical countries (e.g., in India, Uganda, Sudan, and Mexico), with up to tens of thousands affected (Dalton et al., 2013; Kamar et al., 2012). Approximately two billion people (one-third of the world population)
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Another group has recently found
2018-10-23
Another group has recently found that miRNA-146a, by targeting of TRAF6, could suppress of M1 marker UNC0638 in the context of tuberculosis (). The current work from He and colleagues extend these findings by showing that miRNA-146 expression by macrophages can be regulated by type 2 cytokines and
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mek162 We hypothesize that filtration is
2018-10-23
We hypothesize that filtration is also causing stripping of merozoite surface proteins. Recent work has shown that merozoites can recruit the soluble complement regulator factor H (). We are concerned that filtration could also strip factor H or other complement regulators off merozoites making them
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In a plenary session dedicated to new
2018-10-23
In a plenary session dedicated to new technologies, Melissa H. Little from the University of Melbourne (Melbourne, Australia), discussed the generation of kidney organoids from hPSCs and posed the question: where to from here? Approximately 10% of Australian\'s suffer from chronic kidney disease, dr
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The nuclear factor one NF family consists of four
2018-10-23
The nuclear factor one (NF1) family consists of four site-specific transcription factors (NfiA, NfiB, NfiC, and NfiX) that play a large role in the development of a number of organs systems such as the lung and buy AV-951 (Grunder et al., 2002; Harris et al., 2015; Hsu et al., 2011; Steele-Perkins e
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br Funding Sources Lundbeck Foundation Center
2018-10-23
Funding Sources Lundbeck Foundation Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS) (R25-A2701 and R155-2013-16337), Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Mental Health Services, Capital Region of Denmark, and Faculty of
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High oxidative stress and DNA damage activity are
2018-10-23
High oxidative stress and DNA damage activity are increased, while the anti-oxidant enzyme levels are decreased in MM patients (Mehdi et al., 2013). Several free radical drugs, such as As2O3 and ascorbic acid, have been used to treat MM, in which As2O3 generates ROS while ascorbic influenza m2 prote
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br Cutaneous Microbiome in Inflammatory Skin Diseases The
2018-10-23
Cutaneous Microbiome in Inflammatory Skin Diseases The skin acts as an important interface between the organism and the external environment, but also represents an ecosystem providing distinct niches for microbial communities. Next-generation-sequencing approaches used to characterize the cutane
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Conflict of Interest br With about
2018-10-23
Conflict of Interest With about 3–5 million severe cases and 250.000–500.000 deaths yearly, seasonal influenza infections form a constant and serious threat to the human population (). In addition, new influenza virus strains, often originating in birds or pigs, may cross the species barrier to h
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Although the beneficial effects of LXR signaling
2018-10-23
Although the beneficial effects of LXR signaling have been suggested to play a key role in vascular diseases such as atherosclerosis and diabetes, the mechanism of action in which LXR activation influences inflammation and cholesterol metabolism remains an active area of investigation. LXR activity
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BCG has been integrated into the Expanded Immunization
2018-10-23
BCG has been integrated into the Expanded Immunization Program of WHO since 1974 and neonatal vaccination with BCG is still used to prevent TB in countries with a high burden of TB (Marais et al., 2016). Correspondingly, adolescents and adults with LTBI always occur epidemiologically following inocu
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br Acknowledgments We are very
2018-10-23
Acknowledgments We are very grateful to Sol Enriquez, Antonio Fernández Cordeiro, Sole Bastos, Manolo Alonso, Carlos del Río, Pepe Piñeiro, Rubén Portas, Emilio Martínez Sabarís and other members of the bird ringing group Anduriña for truly enjoyable journeys of bird ringing and “grooming”, seaso
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br Acknowledgments This work was supported by
2018-10-23
Acknowledgments This work was supported by National Natural Science Fund of China (Grant no. 61375079). Data The subsequent 52 files are for the specific environmental conditions, under which the six layer configurations are examined. The 52 files are the production of 13 climates and four oc
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Since the different terrorist attack cases have been occurre
2018-10-22
Since 1968, the different terrorist attack cases have been occurred [2]. To protect the naval vessel from these threats, the structure has to be supported by shock wave mitigation methods. Regarding to the good mechanical characteristics of the composite materials, they have varieties of application
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