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The tests performed through the GMM
2018-10-30
The tests performed through the GMM model reveal that the model statistical properties have been respected. The Hansen and Sargan tests, which check if instruments used and additional instruments required by the GMM system are valid, are satisfied. Finally, we also include the Arellano and Bond (199
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br It has been recognised
2018-10-30
It has been recognised that up to 25% of breast cancer overexpresses the transmembrane human epidermal growth factor receptor 2 (HER2), which, in the absence of treatment, is associated with an adverse prognosis for patients . The monoclonal antibody trastuzumab, which targets the HER2 receptor, h
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We hypothesized that elderly have an augmented
2018-10-30
We hypothesized that elderly have an augmented inflammatory response associated with an impaired immune response leading to immune paralysis after a severe burn. We could not confirm our hypothesis, but we found that during the early phases after burn elderly were hypo-inflammatory with significantl
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Sennoside A We next evaluated the profile of hepcidin concen
2018-10-30
We next evaluated the profile of hepcidin concentrations over a 3-month period after exposure to and treatment of febrile clinical malaria. In agreement with other studies in African children we found that concentrations were initially very high (Howard et al., 2007; de Mast et al., 2009; Casals-Pas
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It is clear that the
2018-10-30
It is clear that the Tf–Tfr1 interaction is the high affinity iron acquisition system. In order to identify the role of Tfr1 and iron deficiency on specific cell types, Andrews and colleagues generated tissue-specific deletions of the gene encoding Tfr1 (). Several years ago the authors showed that
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The open label randomised controlled WOEST trial Dewilde
2018-10-30
The open-label, randomised, controlled WOEST trial (Dewilde et al., 2013) suggested that patients undergoing PCI and are on treatment with warfarin (only two-thirds had AF) should be managed by a combination of warfarin and clopidogrel for 1year post PCI and then with warfarin indefinitely. This was
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The most common risk factors associated with stroke eg heart
2018-10-30
The most common risk factors associated with stroke (eg, BI2536 Supplier failure, hypertension, diabetes, age, prior stroke) were initially identified from treatment naïve cohorts of randomised trials conducted 2 decades ago (Lip & Lane, 2015a). These trials only randomised 65 or in presence of an
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Stratifying patients according to the toxicity risk and
2018-10-30
Stratifying patients according to the toxicity risk and modulating EBRT dose would provide a valuable tool for personalized EBRT (). Many efforts have been made to develop assays capable of predicting susceptibility for the development of radiation injury that finally allow customization of EBRT pro
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The objective was to understand
2018-10-29
The objective was to understand the buy Pitolisant hydrochloride of this organism across Europe and to get insight into the geographical and temporal evolution of the different genotypes. The diversity of P. jirovecii isolates responsible for PCP across different European countries (n=12) was inves
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br Codon usage bias and pathway level
2018-10-29
Codon usage bias and pathway level functions CAI was demonstrated to be positively correlated to relative protein abundance in Leishmania[1]. Hence, assuming CAI to be a predictor of protein expression, we compared CAI values of A769662 belonging to different pathways/processes. For this comparis
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br Materials and methods br Results br Acknowledgment The
2018-10-29
Materials and methods Results Acknowledgment The experiments described in this data article are a limited part of our global research project on drug discovery and target identification in tropical neglected diseases, which we conducted with the financial support of the Ministry of Educatio
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br Data Dataset provided in this article shows the NMR
2018-10-29
Data Dataset provided in this article shows the NMR spectra for compounds extracted from native Australian plants species Pilidiostigma glabrum, Myoporum montanum, Geijera parviflora, and Rhodomyrtus psidioides. In addition to collagen synthesis [5], additional analysis was performed to determine
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br Acknowledgements This study was
2018-10-29
Acknowledgements This study was supported by a Grant from the Smoking Research Foundation (URL: http://www.srf.or.jp/english/index.html), Grant-in-Aid for Scientific Research on Innovative Areas 26118701, 26120701(Y.O.), and Grant-in-Aid for Young Scientists (A) 25713043 (Y.O.) from the Ministry
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br Experimental design materials and methods IgM heavy chain
2018-10-29
Experimental design, materials and methods IgM heavy chain variable domain-encoding gene repertoires were isolated by RT-PCR from transcriptomes of PB and BM collected out of season of most seasonal buy GDC-0152 from six allergic subjects [3]. Ethical approval and informed consent had been obtai
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Here we present the first observation
2018-10-29
Here, we present the first observation of an interaction between dyslexia risk kit inhibitor and the encoding of sounds in the auditory brainstem in humans. The small number of participants makes it necessary to consider these observations as preliminary with a need for replication. To date, no stu
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