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br Materials and methods br Results and discussions br
2018-11-06
Materials and methods Results and discussions Conclusion The capability of the CTs extracts to scavenge free radicals in different systems, indicating that they may be useful therapeutic agents for treating various chronic diseases which are more related to oxidative stress associated disea
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br Materials and methods br Results and discussion All
2018-11-06
Materials and methods Results and discussion All isolates produced PCR amplicon with the COAG2 and COAG3 primers (Fig. 1). The agarose gel analysis of the liothyronine sodium manufacturer products showed ten different sizes, ranging from approximately 500 to 1000bp. The product sizes of 800,
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Previously we demonstrated that injured kidney tissues can i
2018-11-06
Previously, we demonstrated that injured kidney tissues can induce bone marrow stromal adenosine receptor to differentiate into renal tubular epithelial-like cells in vitro and in vivo (Qian et al., 2008). However, another work reported that the beneficial effects of BMSCs are primarily mediated by
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hESC NPCs and hfNPCs induced different PBMC
2018-11-06
hESC-NPCs and hfNPCs induced different PBMC proliferative responses, despite relatively similar expression levels of HLA, co-stimulatory and adhesion molecules. Multiple other factors that are produced by NPCs and may contribute to the regulation of the immune response such as inducible nitric oxide
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A recent study on hair cell
2018-11-06
A recent study on hair cell differentiation in adult animals with hair cell loss after Notch inhibition did not identify the supporting ll-37 that responded (Mizutari et al., 2013). The results we describe here are surprising, because we did not expect that the transdifferentiation of supporting ce
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Understanding of potential mechanisms involved in the
2018-11-06
Understanding of potential mechanisms involved in the initial inherent neuronal bias of cultures and then using small molecules to alter this bias towards astrocyte lineages will enable uniform and faster processes to generate astrocytes. Here we explore the epigenetic mechanism that maintains the p
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br Introduction Breast cancer is a
2018-11-06
Introduction Breast cancer is a heterogeneous disease characterized by at least eighteen histopathological and six distinct molecular subtypes, making it extremely difficult to treat (Sørlie et al., 2001). This phenotypic diversity is considered to reflect the epithelial lineage from which a give
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To examine the proliferative and differentiative capacities
2018-11-06
To examine the proliferative and differentiative capacities of the GSpos and GSVpos populations, we performed limit dilution analysis to determine the clonogenic frequency of single flow sorted Anti-cancer Compound Library (Elliott et al., 2011). Under these adherent culture conditions, the GSpos ce
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br Lineage tracing tools for
2018-11-06
Lineage tracing tools for investigating stem cell biology The investigation of cell lineage involves labeling cgrp antagonist of interest, then tracing the destiny of their progeny. The reliance on the presence of cell markers alone to infer the origin or fate of a cell population is fallible, as
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We have demonstrated that neuregulin induced proliferation o
2018-11-06
We have demonstrated that neuregulin-induced proliferation of differentiated adult mouse and rat cardiomyocytes occurs primarily in the mononucleated portion (Bersell et al., 2009). Most adult zebrafish cardiomyocytes are mononucleated, which is consistent with their significant proliferative activi
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CXCL has been previously identified as an estrogen
2018-11-06
CXCL12 has been previously identified as an estrogen-regulated gene in estrogen receptor (ER)-positive ovarian and breast cancer Phenyl sulfate (Jaerve et al., 2012). Here we show that in the endometrium, E2 significantly increased CXCL12 expression, suggesting a mechanism by which stem cells are r
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Epiretinal transplantation does not involve retinal detachme
2018-11-06
Epiretinal transplantation does not involve retinal detachment and may cause less trauma to the retina as compared with subretinal cell delivery. However vitreous detachment in patients causes increased photopsias, floaters and increased risk of retinal detachment and macular holes (de Smet et al.,
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br Materials and methods br Author
2018-11-06
Materials and methods Author disclosure statement Acknowledgments We are grateful to Prof. Angel Raya for his help and advice with iPS cell generation. This work was supported by grants from the “Centro de Investigación Biomédica en Red en Enfermedades Raras” (CIBERER) (grant 13-717/132.05
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WP1130 Main Text In this issue of Stem Cell Reports two
2018-11-05
Main Text In this issue of Stem Cell Reports, two critically important studies describe negative results of a neural stem cell (NSC) product (HuCNS-SC) intended for clinical use in a model of cervical spinal cord injury (SCI) (Anderson et al., 2017) and in a model of Alzheimer’s disease (Marsh et a
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Introduction The phospho proteome in
2018-11-05
Introduction The phospho-proteome in pluripotent stem tgf beta receptor inhibitor has been extensively and systematically studied (Van Hoof et al., 2012), and has uncovered phosphorylated residues on pluripotency factors that play important roles in establishing and maintaining pluripotency. Despi
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